特意上wiki看了看 这样写
Health concerns
Main article: Aspartame controversy
Aspartame has been the subject of controversy regarding its safety and the circumstances of its approval by the American FDA and European FSA. Aspartic acid, into which aspartame is metabolized, is a known NMDA receptor antagonist. Aspartame itself has been shown to have antinociceptive properties through effecting NMDA receptors in mice. Some studies have also recommended further investigation into possible connections between aspartame and negative effects such as headaches, brain tumors, brain lesions, and lymphoma.[16][17][18] These findings, combined with possible conflicts of interest involving CEO Donald Rumsfeld in the approval process, have engendered vocal activism regarding the possible risks of aspartame.[19][20]
貌似阿斯巴甜和头痛和其他大脑疾病的关系还没有明了